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In a large pot, bring water to a boil; add macaroni. Cook according to package directions. Drain; set aside.
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In the same pot, brown ground beef over medium-high heat until all pink is gone. Drain grease. Add 1/2 cup Manwich sauce, beans, pepper, cayenne, garlic powder, adobo seasoning, and jalapeno. Stir until well combined. Reduce heat to medium-low and simmer for 5 to 8 minutes.
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Add 1/4 cup Manwich sauce and macaroni. Stir to combine, until pasta is well coated.
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Sprinkle cheese over the top of the dish. Cover pot, and turn off heat. Let sit for 2 to 3 minutes, until cheese melts. Serve warm.